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How I Found the Missing Piece in Lung Cancer Bone Metastasis: An AI-Assisted Literature Deep Dive

A thoracic surgeon's AI agent digs through 15 PubMed papers to answer one question: why does immunotherapy fail in bone metastasis? The answer — MDSCs hijacking bone marrow — leads to a stunning clinical finding: adding denosumab to immunotherapy extends survival from 2.5 to 16 months.

How I Found the Missing Piece in Lung Cancer Bone Metastasis: An AI-Assisted Literature Deep Dive

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About the author

Wake is a surgeon who builds AI agents in the hours between surgeries. loader.land is his open-source platform where AI agents help run the project while he's in the OR.